This time of year many people are looking to drop excess weight. In their desire to see rapid results, many start a supplement program such as AdvoCare®. Glucophage, Glucophage XR (metformin) dosing, indications, interactions, adverse effects, and more. Black Box Warnings. Lactic acidosis is a rare, but potentially severe, consequence of therapy with metformin; it is characterized by elevated blood lactate levels (> 5 mmol/L), decreased blood p. H, electrolyte disturbances with an increased anion gap, and an increased lactate/pyruvate ratio; when metformin is implicated as the cause of lactic acidosis, metformin plasma concentrations > 5 mcg/m. L are generally found. Patients with CHF requiring pharmacologic management, in particular those with unstable or acute CHF who are at risk for hypoperfusion and hypoxemia, are at an increased risk for lactic acidosis; the risk for lactic acidosis increases with the degree of renal dysfunction and the patient. INDICATIONS AND USAGE GLUCOPHAGE (metformin hydrochloride) Tablets is indicated as an adjunct to diet and exercise to improve glycemic control in adults and children. What is, what is used for, dose, side effects, brands. List of brands containing metformin This page contains list of brands of authorized pharmaceutical specialties of the active ingredient metformin in the countries listed below. So that, in no case can take decisions based on the information contained on the page. MEDIZZINE is not responsible for any damage arising from the information provided, which may be incomplete or outdated. Metformin is indicated for the treatment of type 2 diabetes mellitus adult when blood glucose values are not adequately controlled with diet and exercise, especially in overweight patients. Although metformin can help you lose weight, it's not as effective as diet and lifetsyle changes. The Diabetes Prevention. I've been taking 500 mg/day of metformin. Just wondering if any of you have taken this, and if so, have you experienced any weight loss? This drug can be used as monotherapy or in combination with insulin when this medicine is insufficient to achieve good glycemic control or with other antidiabetic. This substance belongs to the biguanide class. It works by helping the body better use the insulin produced in the pancreas, making more efficient the role of this organ. Metformin: Nonglycemic Effects and Potential Novel Indications. Abeer Anabtawi, MD; John M. The coadministration of linagliptin and metformin has been studied in patients with type 2 diabetes mellitus inadequately controlled on diet and. Non-Alcoholic Fatty Liver Disease (NAFLD) Nutritional and Supplemental Support. Glycomet (Metformin Tablets) and Exermet XR ((Metformin SR) are used to treat type 2 diabetes mellitus in adults, when diet and exercise alone does not result. Medizzine recommends consulting your doctor if you are unsure (or you do not know) why you have been given metformin. Other ingredients of available commercial presentations: The active substance is metformin hydrochloride. The other ingredients may include povidone K3. A), maize starch, colloidal anhydrous silica, titanium dioxide (E1. VA6. 4 co polyvidone. Warning: The composition of the various presentations may vary from one country to another. We recommend you consult the information provided by your local supplier. Some specialties with metformin contain lactose. If your doctor has told you to have an intolerance to some sugars, consult him before taking this medicine, after checking that it contains this sugar. Do not use metformin. If you are allergic (hypersensitive) to metformin or any of the other ingredients of the medicinal product prescribed to you. If you think may be allergic, ask your doctor. Allergy symptoms may include: - Asthma attacks with shortness of breath, audible wheezing or rapid breathing.- More or less sudden swelling of the face, lips, tongue or elsewhere in the body. It is especially critical if it affects the vocal cords.- Hives, itching, rash- Anaphylactic shock (loss of consciousness, paleness, sweating, etc.). Nor you should take this medicine: - If you suffer Diabetes Mellitus well controlled with diet and exercise,- If you suffer Diabetes Mellitus well controlled with insulin,- If you have diabetic ketoacidosis or diabetic pre- coma- If you are in a situation of loss of body fluids, dehydration, shock or major bleeding- If you suffer a severe liver disease- if you have an alcohol intoxication- if you have a pancreatitis- In the case of suffering severe infections or severe cardiovascular and pulmonary disease (heart attacks, recent pulmonary embolism, heart failure, etc.). Be sure to consult your doctor if: - You need a scan as a radiography or a scanner involving blood injection of contrast media containing iodine.- You need major surgery. You should stop taking metformin for a certain time period before and after the examination or surgery. Your doctor will decide if you need any other treatment during this time. It is important to accurately follow your doctor's instructions. Take special care with. Metformin may cause a very rare but serious complication, called lactic acidosis, especially if your kidneys are not working properly. Symptoms of lactic acidosis are vomiting, abdominal pain with cramps, a general feeling of discomfort with severe fatigue, and difficulty breathing. If this happens, you may need immediate treatment. Stop. taking metformin and tell your doctor right away. Metformin alone does not cause hypoglycemia (a too low glucose blood level ). However, there is a risk of hypoglycemia if you take metformin together with other medicines to treat diabetes (such as sulfonylureas, insulin or glinides), Also, these drugs taken alone may cause hypoglycemia. If you have symptoms of hypoglycemia, such as weakness. Remember that your doctor has prescribed this medicine only for you. Never give it to someone else. If in doubt, consult your doctor. Taking other medicines. Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including herbal products or drugs obtained without a prescription. Especially, tell your doctor or pharmacist if you are taking: If you need a blood injection of contrast media containing iodine, for example for examinations such as X- rays or a scanner, you should stop taking metformin for a certain period of time before and after scanning. Tell your doctor if you use any of the following medicines and metformin at the same time. You may need tests more frequent blood glucose or your doctor may adjust the dosage of metformin: - Angiotensin- converting enzyme inhibitors (ACE inhibitors)) (used to treat diverse diseases of the heart and blood vessels, including high blood pressure and heart failure).- Diuretics (used to remove water from the body).- Beta- 2 agonists, such as salbutamol or terbutaline (used to treat asthma).- Corticosteroids (prednisone, dexamethasone, deflazacort, etc.), used to treat various diseases, such as severe inflammation of the skin or asthma). Use with food and beverages. Do not drink alcohol while taking this medicine. Alcohol may increase the risk of lactic acidosis especially if you have liver problems or if you are malnourished. This also includes medicines that contain alcohol. Consult your doctor or pharmacist before taking any medicine. Special physiological situations. Pregnancy and lactationalways consult your doctor or pharmacist before taking any medicine during pregnancy or lactation. If you are pregnant or planning to become pregnant, you should tell your doctor before starting or continuing treatment with metformin. Your doctor can guide you about the available alternatives. If you are prescribed metformin while nursing your child, you should consult your doctor. Children. Metformin should not be used in children. Use in elderly. There seem no particular problems in the elderly unless there are concurrent diseases which could contraindicate to use it. Driving and using machines. Metformin alone does not cause hypoglycemia (a too low concentration of blood glucose). This means it will not affect your ability to drive or operate machinery. However, you should take a special care if you take metformin together with other medicines to treat diabetes that can cause hypoglycemia (such as sulfonylureas, insulin, glinides). The symptoms of hypoglycemia include weakness, dizziness, increased sweating, increased heartbeats, vision disorders or difficulty concentrating. Do not drive or operate machinery if. Follow carefully instructions of use of metformin provided from your doctor. Consult your doctor or pharmacist when in doubt. Follow the instructions of the physician in preference to those given in this website, which may be different. Ask your doctor to explain any aspect that you do not understand, contained in the instruction leaflet that comes with the medicine. Metformin can not replace the benefits of a healthy lifestyle. Continue following any advice about diet that your doctor has given you, and practice physical activities regularly. The maximum daily dose is 2. Treatment of children between 1. Adults Starting dose: 5. The maximum daily dose is 3. If you also use insulin, your doctor will tell you how to start taking metformin. Monitoring- Your doctor will adapt your dose of metformin to your concentration of glucose in the blood. Be sure to talk regularly with your doctor. This is particularly important for children, adolescents, or if you are an elderly patient.- Your doctor will also check at least once a year how well your kidneys work. You may need more frequent checks if it is an older person or if your kidneys are not functioning normally. Taking metformin. Take the tablets with meals or after them. This will prevent suffering side effects affecting your digestion. Do not crush or chew the tablets. Swallow each tablet with a glass of water.- If you take one dose a day, take it in the morning (at breakfast).- If you take two doses a day, take it in the morning (breakfast) and evening (dinner).- If you take three doses a day, take in the morning (breakfast), at noon (lunch) and evening (dinner). If you think the effect of the medicine is too strong or too weak, consult your doctor. If you have any further questions on the use of this product, ask your doctor or pharmacist. If a doctor prescribes another medicine, tell you are taking metformin. Check with your doctor regularly developments of disorder that motivates the use of metformin. Maybe there is some reason that prevented you properly receive the indicated doses and induce your doctor to erroneous conclusions about treatment. Do not restart treatment with metformin at your own risk without first talking to your doctor, nor encourage its use by another person, even if have the same symptoms you have. Nor is it advisable to interrupt or reduce the dose without considering the opinion of your doctor. If you feel unwell during treatment with metformin, immediately consult your doctor. If you take more than you should: If you have taken more metformin than you should, you may experience lactic acidosis. Symptoms of lactic acidosis include vomiting, abdominal cramping pain, a sense of discomfort with severe fatigue and difficulty breathing. Immediately consult your doctor or pharmacist. In the case of overdose, immediately consult your doctor or pharmacist or go to the emergency department of the nearest hospital. Take the container with you, even if it is empty. If you forget to take metformin. Do not take a double dose to make up the missed dose. Take the next dose at the normal time. If you have any further questions on the use of this product, ask your doctor or pharmacist. Like all medicines, metformin can cause side effects although not everybody gets them. The frequency of side effects is classified into: Very common: affect 1 out of 1- 1.
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